Which immune globulin is administered to Rh negative mothers with Rh positive newborns within 72 hours of delivery?

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The administration of Rh0(D) immune globulin to Rh negative mothers with Rh positive newborns is a crucial preventative measure to avoid Rh sensitization. This process helps to prevent the mother's immune system from producing antibodies against Rh positive blood cells, which could lead to hemolytic disease of the newborn (HDN) in future pregnancies.

When an Rh negative mother delivers an Rh positive baby, there's a risk that fetal Rh positive blood can enter the maternal circulation, especially during delivery. If this occurs, the mother's immune system may recognize the Rh positive cells as foreign and produce antibodies against them. In subsequent pregnancies with Rh positive babies, these maternal antibodies can cross the placenta and attack the fetal red blood cells, causing serious complications.

By administering Rh0(D) immune globulin within 72 hours of delivery, it effectively neutralizes any Rh positive fetal cells in the mother's bloodstream, thus preventing her immune system from mounting a response. This prophylactic treatment is vital in ensuring the health of the mother in future pregnancies and the safety of her subsequent children.

The other options provided do not serve this purpose, as they are designated for other immunization needs and situations unrelated to the management of Rh factor incompatibility.

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